Segmented Process Systems
1.Pertussis Vaccine Cultivation SystemCore Design:
The aspect ratio of the reactor is precisely controlled between 1.2 and 2.1, customized according to the growth characteristics of Bordetella pertussis cultivation; it adopts an integrated structure of surface aeration and deep aeration, supporting the automatic flow ratio adjustment of AIR and O₂ to ensure the stability of dissolved oxygen during strain cultivation.
2.HPV Vaccine Production System
Compliance Design:
Adopts Grade A aseptic standard architecture, supporting Clean-in-Place (CIP) and Sterilization-in-Place (SIP); the tank body and material contact components are all made of AISI 316L stainless steel, with an inner surface polishing precision of 0.2μm to eliminate the risk of contamination.
Process Control:
Integrates full-dimensional sensors such as temperature, pressure, flow, pH, DO, OD, and viable cell detection to realize real-time monitoring and automatic regulation of the production process.
Core Advantages:
It features a highly automated production process and advanced process system technology, which is suitable for the large-scale production needs of HPV vaccines.
3.COVID-19 Vaccine Multi-Technology Adaptation SystemTechnology Route Coverage:
Compatible with multiple COVID-19 vaccine production processes, including inactivated vaccines, recombinant subunit vaccines, adenovirus vector vaccines, live-attenuated influenza virus vector vaccines, and nucleic acid vaccines.
Core Modules:
Provides key process module equipment such as buffer preparation system, harvest/inactivation system, and CIP unit for production workshops, supporting the standardized implementation of the entire vaccine production process.
Core System Parameters
|
Item |
Technical Specifications |
|
Material (Material Contact) |
AISI 316L Stainless Steel |
|
Inner Surface Polishing Precision |
0.2μm |
|
Compliance Standards |
Complies with GMP and EU production regulations |
|
Aeration Control |
Integrated surface + deep aeration; automatic AIR/O₂ flow ratio adjustment |
|
Process Monitoring Sensors |
Temperature, Pressure, Flow, pH, DO, OD, Viable Cell Detection |
|
Cleaning/Sterilization Method |
Clean-in-Place (CIP), Sterilization-in-Place (SIP) |
|
Pertussis Reactor Aspect Ratio |
1.2-2.1 |
System Value
The Vaccine-Specific GMP Production System focuses on process adaptability, compliance, and automation. It helps vaccine manufacturers achieve efficient, stable, and globally standardized large-scale production, and is a professional equipment solution for human vaccine production in the biopharmaceutical field.
