High-Performance Cell Line Screening System
Product Overview
Breakthrough R&D Bottlenecks, Accelerate Elite Strain Discovery
The High-Performance Cell Line Screening System is an "intelligent, integrated screening platform" specifically designed for synthetic biology, metabolic engineering, and biopharmaceutical R&D. It integrates "high-density micro-culture, real-time online monitoring, and AI-driven phenotypic analysis", reducing traditional strain screening cycles from weeks or even months to mere days. It dramatically enhances the efficiency and success rate of discovering "high-yield, robust, and high-performance" engineered strains. This system is your core equipment for rapidly identifying the optimal candidates from vast genetic libraries and seizing a competitive R&D advantage.
Core Advantages
| Strengths | Describe |
| High throughput and parallelization | Supports ultra-high-throughput culture and screening at the level of 96-well plates, 384-well plates, or even microfluidic chips. Each run can process thousands of clones in parallel, vastly expanding the screening library capacity and statistical significance. |
| online monitoring of the whole process | Integrates non-invasive optical sensors (pH, DO, biomass) to monitor cell growth, substrate consumption, and product formation kinetics in each microwell in real-time, providing full-cycle, high-time-resolution phenotypic data. |
| AI Intelligent Analysis and Decision | Built-in AI algorithms perform automatic clustering, correlation analysis, and predictive modeling on multi-dimensional phenotypic data, automatically identifying optimal phenotypic clusters and recommending priority validation clones, reducing reliance on empirical judgment for more objective and precise screening. |
| Flexibility and scalability | Modular design allows for easy integration with "automated liquid handling workstations, colony pickers, and downstream analysis equipment (e.g., HPLC, mass spectrometers)", seamlessly fitting into your existing automated R&D pipeline. |
| Data integrity and traceability | Compliant with data integrity requirements such as "21 CFR Part 11". All raw data, process parameters, and analysis results are automatically stored and linked, generating complete, traceable electronic lab records to meet compliance audit needs. |
Technical Specifications
| Parameter category | Technical Specifications |
| culture flux | Compatible with standard 24-well, 96-well, and 384-well plates; Optional microfluidic chip module (>10,000 independent units per experiment) |
| online monitoring parameter | pH, Dissolved Oxygen (DO), Biomass (OD), Fluorescence Intensity (e.g., GFP/RFP), Metabolite Concentration (via specific indicators) |
| culture control | Temp Range: Ambient + 4°C ~ 60°C (Uniformity ±0.2°C);Agitation: 0-1500 rpm (programmable);Gas Control: Independent O₂, CO₂, N₂ mixture regulation for each module |
| data acquisition | Acquisition Frequency: Up to 1 time per minute;Data Interface: Ethernet, RS-232, Wireless (Optional) |
| software platform | Dedicated Control & Analysis Software: Devotion-ScreenPro™ V2.0. Supports Design of Experiments (DOE), remote monitoring, AI data analysis, and visual report generation. |
| Physical size | Main Unit: W 800mm × D 750mm × H 600mm;Weight: ~85 kg |
| power requirement | AC 220V ±10%, 50/60Hz, Max. Power 2.5 kW |
Application Scenarios
Support & Services
We deliver not just an instrument, but a complete screening solution:
